Cobalt-catalyzed hydrofluorination of unactivated olefins: a radical approach of fluorine transfer.

Authors :: Shigehisa H
Nishi E
Fujisawa M
Hiroya K
Source :: Organic letters [Org Lett] 2013 Oct 18; Vol. 15 (20), pp. 5158-61. Date of Electronic Publication: 2013 Sep 30.
Publication Year :: 2013
Abstract: Catalytic hydrofluorination of olefins using a cobalt catalyst was developed. The exclusive Markovnikov selectivity, functional group tolerance, and scalability of this reaction make it an attractive protocol for the hydrofluorination of olefins. A preliminary mechanistic experiment showed the involvement of a radical intermediate.

Subjects :: Catalysis
Free Radicals chemistry
Hydrocarbons, Fluorinated chemistry
Molecular Structure
Alkenes chemistry
Cobalt chemistry
Fluorine chemistry
Hydrocarbons, Fluorinated chemical synthesis
Organometallic Compounds chemistry

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