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Fat accretion in a subpopulation of hepatocytes as a strategy to protect the whole liver against oxidative stress and lipotoxicity.
- Source :
-
Clinics and research in hepatology and gastroenterology [Clin Res Hepatol Gastroenterol] 2013 Dec; Vol. 37 (6), pp. 553-5. Date of Electronic Publication: 2013 Sep 25. - Publication Year :
- 2013
-
Abstract
- Fatty liver can be induced by obesity, some drugs and alcohol intoxication. In this liver lesion, lipid accumulation can involve only some hepatocytes but the significance of this cell-to-cell heterogeneity is unknown. In a recent work, Dr Pol et al. propose that high-fat hepatocytes could protect the cell population against oxidative stress and lipotoxicity.<br /> (Copyright © 2013 Elsevier Masson SAS. All rights reserved.)
- Subjects :
- Animals
Hepatocytes cytology
Lipid Metabolism
Lipids chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 2210-741X
- Volume :
- 37
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Clinics and research in hepatology and gastroenterology
- Publication Type :
- Academic Journal
- Accession number :
- 24075194
- Full Text :
- https://doi.org/10.1016/j.clinre.2013.08.005