Back to Search
Start Over
SIRS is valid in discriminating between severe and moderate diabetic foot infections.
- Source :
-
Diabetes care [Diabetes Care] 2013 Nov; Vol. 36 (11), pp. 3706-11. Date of Electronic Publication: 2013 Sep 23. - Publication Year :
- 2013
-
Abstract
- Objective: This retrospective, single-center study was designed to distinguish severe diabetic foot infection (DFI) from moderate DFI based on the presence or absence of systemic inflammatory response syndrome (SIRS).<br />Research Design and Methods: The database of a single academic foot and ankle program was reviewed and 119 patients were identified. Severe DFI was defined as local infection associated with manifestation of two or more objective findings of systemic toxicity using SIRS criteria.<br />Results: Patients with severe DFI experienced a 2.55-fold higher risk of any amputation (95% CI 1.21-5.36) and a 7.12-fold higher risk of major amputation (1.83-41.05) than patients with moderate DFI. The risk of minor amputations was not significantly different between the two groups (odds ratio 1.02 [95% CI 0.51-2.28]). The odds of having a severe DFI was 7.82 times higher in patients who presented with gangrene (2.03-44.81) and five times higher in patients who reported symptoms of anorexia, chills, nausea, or vomiting (2.22-11.25). The mean hospital length of stay for patients with severe DFI was ∼4 days longer than for patients with moderate DFI, and this difference was statistically significant.<br />Conclusions: SIRS is valid in distinguishing severe from moderate DFI in hospitalized patients. Patients with severe DFI, as by manifesting two or more signs of systemic inflammation or toxicity, had higher rates of major amputation and longer hospital stays and required more surgery and more subsequent admissions than patients who did not manifest SIRS.
- Subjects :
- Aged
Amputation, Surgical
Diabetic Foot complications
Female
Gangrene surgery
Humans
Male
Middle Aged
Patient Admission
Retrospective Studies
Severity of Illness Index
Systemic Inflammatory Response Syndrome complications
Diabetic Foot diagnosis
Length of Stay
Systemic Inflammatory Response Syndrome diagnosis
Subjects
Details
- Language :
- English
- ISSN :
- 1935-5548
- Volume :
- 36
- Issue :
- 11
- Database :
- MEDLINE
- Journal :
- Diabetes care
- Publication Type :
- Academic Journal
- Accession number :
- 24062324
- Full Text :
- https://doi.org/10.2337/dc13-1083