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Could polymerase chain reaction tests on conjunctival swabs be useful to diagnose herpetic keratitis?
- Source :
-
Enfermedades infecciosas y microbiologia clinica [Enferm Infecc Microbiol Clin] 2014 Jan; Vol. 32 (1), pp. 28-30. Date of Electronic Publication: 2013 Sep 20. - Publication Year :
- 2014
-
Abstract
- Introduction: Diagnosis of HSV-1 keratitis (HK) is frequently based on clinical findings. Invasive specimens (corneal scrapings, biopsies) are required for microbiological diagnosis.<br />Methods: Corneal scrapings and conjunctival swabs were collected on patients with/without clinical suspicion of HK from 2007 to 2012.<br />Results: The sensitivity, specificity, positive and negative predictive values for conjunctival swabs by PCR was 77.8, 92.1, 84.4 and 88.3, respectively.<br />Discussion: Conjunctival swabs by PCR may help in the diagnosis of HK, despite the limited sensitivity.<br /> (Copyright © 2013 Elsevier España, S.L. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1578-1852
- Volume :
- 32
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Enfermedades infecciosas y microbiologia clinica
- Publication Type :
- Academic Journal
- Accession number :
- 24060450
- Full Text :
- https://doi.org/10.1016/j.eimc.2013.07.005