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The Wedensky test predicts malignant ventricular arrhythmias after myocardial infarction.
- Source :
-
Scandinavian cardiovascular journal : SCJ [Scand Cardiovasc J] 2013 Oct; Vol. 47 (5), pp. 256-62. - Publication Year :
- 2013
-
Abstract
- Objectives: Better tools are needed for detection of future malignant ventricular arrhythmias post myocardial infarct (MI). Wedensky Modulation (WM) is a new semi-invasive method: A short low-amplitude electrical impulse is applied synchronized to the QRS between a precordial and dorsal thoracic patch, and changes in the following QRS-T are registered.<br />Design: A total of 357 (MI) ICD patients underwent WM testing. QRS-T wavelet analysis provided WM Indexes for the QRS complex (WMI-R) and T wave (WMI-T). Outcome was the time to first occurrence of appropriate device therapy for ventricular arrhythmia. Patients were followed at 6-month intervals for 2 years.<br />Results: No arrhythmia was induced by the testing. Two-year appropriate arrhythmia treatment occurred in 35% (WMI-R positive) versus 25% (WMI-R negative, p = 0.014), and. 45% versus 26% (p = 0.001) for WMI-T positive versus negative. Two-year event rates of WMI-R or WMI-T positive versus WMI-R and WMI-T negative were 36% versus 22% (p = 0.004). In Cox proportional hazard model, the combination of WMI-R and WMI-T was the only statistically significant event predictor (p = 0.003).<br />Conclusion: Potentially life-threatening ventricular arrhythmic events could be predicted by the WM test. In combination with other risk factors WMI may be useful in these patients.
Details
- Language :
- English
- ISSN :
- 1651-2006
- Volume :
- 47
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Scandinavian cardiovascular journal : SCJ
- Publication Type :
- Academic Journal
- Accession number :
- 24050376
- Full Text :
- https://doi.org/10.3109/14017431.2013.831117