Back to Search
Start Over
Characterisation of novel and rare Y-chromosome short tandem repeat alleles in self-declared South Australian Aboriginal database.
- Source :
-
International journal of legal medicine [Int J Legal Med] 2014 Jan; Vol. 128 (1), pp. 27-31. Date of Electronic Publication: 2013 Sep 19. - Publication Year :
- 2014
-
Abstract
- Y-chromosome short tandem repeats (Y-STRs) are used in forensic science laboratories all over the world, as their application is wide and often vital in solving casework. Analysis of an in-house database of South Australian self-declared Aboriginal males held by Forensic Science South Australia (FSSA) using the Applied Biosystem's AmpFℓSTR® Yfiler™ PCR Amplification Kit revealed 43 variant Y-STR alleles at 6 of the 17 loci. All variant alleles were sequenced to determine the exact repeat structure for each. As a high level of admixture has previously been found within the SA Aboriginal database, samples were haplogrouped using Y-SNPs to determine their likely geographical origin. Although a number of variant alleles were associated with non-Aboriginal Y-haplogroups, a high frequency was observed within the Australian K-M9 lineage. Detailed knowledge of these variant alleles may have further application in the development of new DNA markers for identification purposes, and in population and evolutionary studies of Australian Aborigines.
- Subjects :
- Cross-Cultural Comparison
DNA Fingerprinting methods
Genetic Loci genetics
Genetic Markers genetics
Genetic Variation genetics
Haplotypes
Humans
Male
South Australia
Chromosomes, Human, Y genetics
Databases, Genetic
Forensic Genetics methods
Gene Frequency
Genetics, Population
Microsatellite Repeats genetics
Native Hawaiian or Other Pacific Islander genetics
Subjects
Details
- Language :
- English
- ISSN :
- 1437-1596
- Volume :
- 128
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- International journal of legal medicine
- Publication Type :
- Academic Journal
- Accession number :
- 24048501
- Full Text :
- https://doi.org/10.1007/s00414-013-0911-y