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Two new sphingolipids from the leaves of Piper betle L.
- Source :
-
Molecules (Basel, Switzerland) [Molecules] 2013 Sep 12; Vol. 18 (9), pp. 11241-9. Date of Electronic Publication: 2013 Sep 12. - Publication Year :
- 2013
-
Abstract
- Two new sphingolipids, pipercerebrosides A (1) and B (2), were isolated from the leaves of Piper betle L. Their structures, including absolute configurations, were determined by spectroscopic analysis and chemical degradation. These two compounds did not show significant cytotoxic activity against the cancer cell lines K562 and HL-60 in a MTT assay.
- Subjects :
- Drug Screening Assays, Antitumor
Drugs, Chinese Herbal isolation & purification
Drugs, Chinese Herbal pharmacology
HL-60 Cells
Humans
K562 Cells
Methylation
Molecular Structure
Oxidation-Reduction
Sphingolipids isolation & purification
Sphingolipids pharmacology
Drugs, Chinese Herbal chemistry
Piper betle chemistry
Plant Leaves chemistry
Sphingolipids chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 1420-3049
- Volume :
- 18
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- Molecules (Basel, Switzerland)
- Publication Type :
- Academic Journal
- Accession number :
- 24036513
- Full Text :
- https://doi.org/10.3390/molecules180911241