Back to Search Start Over

Broadening the indications for hematopoietic stem cell genetic therapies.

Authors :
Williams DA
Source :
Cell stem cell [Cell Stem Cell] 2013 Sep 05; Vol. 13 (3), pp. 263-4.
Publication Year :
2013

Abstract

The use of recombinant retroviral vectors to effect corrective genetic therapies in hematopoietic stem cells (HSCs) has long been predicted to revolutionize medicine. Two recent papers in Science now show that this technology could be considered as effective as, and perhaps superior to, allogeneic HSC transplants in some rare diseases.<br /> (Copyright © 2013 Elsevier Inc. All rights reserved.)

Subjects

Subjects :
Humans
Male
Cerebroside-Sulfatase genetics
Genetic Therapy methods
Hematopoietic Stem Cell Transplantation
Hematopoietic Stem Cells metabolism
Leukodystrophy, Metachromatic therapy
Wiskott-Aldrich Syndrome therapy
Wiskott-Aldrich Syndrome Protein genetics

Details

Language :
English
ISSN :
1875-9777
Volume :
13
Issue :
3
Database :
MEDLINE
Journal :
Cell stem cell
Publication Type :
Academic Journal
Accession number :
24012366
Full Text :
https://doi.org/10.1016/j.stem.2013.08.006
Full Text Access
View/download PDF

Tools

Authors Abstract Subjects Details