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The prevalence of depression in rheumatoid arthritis: a systematic review and meta-analysis.
- Source :
-
Rheumatology (Oxford, England) [Rheumatology (Oxford)] 2013 Dec; Vol. 52 (12), pp. 2136-48. Date of Electronic Publication: 2013 Sep 03. - Publication Year :
- 2013
-
Abstract
- Objective: There is substantial uncertainty regarding the prevalence of depression in RA. We conducted a systematic review aiming to describe the prevalence of depression in RA.<br />Methods: Web of Science, PsycINFO, CINAHL, Embase, Medline and PubMed were searched for cross-sectional studies reporting a prevalence estimate for depression in adult RA patients. Studies were reviewed in accordance with the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines and a meta-analysis was performed.<br />Results: A total of 72 studies, including 13,189 patients, were eligible for inclusion in the review. Forty-three methods of defining depression were reported. Meta-analyses revealed the prevalence of major depressive disorder to be 16.8% (95% CI 10%, 24%). According to the PHQ-9, the prevalence of depression was 38.8% (95% CI 34%, 43%), and prevalence levels according to the HADS with thresholds of 8 and 11 were 34.2% (95% CI 25%, 44%) and 14.8% (95% CI 12%, 18%), respectively. The main influence on depression prevalence was the mean age of the sample.<br />Conclusion: Depression is highly prevalent in RA and associated with poorer RA outcomes. This suggests that optimal care of RA patients may include the detection and management of depression.
Details
- Language :
- English
- ISSN :
- 1462-0332
- Volume :
- 52
- Issue :
- 12
- Database :
- MEDLINE
- Journal :
- Rheumatology (Oxford, England)
- Publication Type :
- Academic Journal
- Accession number :
- 24003249
- Full Text :
- https://doi.org/10.1093/rheumatology/ket169