Complete agenesis of major salivary glands.

Authors :: Berta E
Bettega G
Jouk PS
Billy G
Nugues F
Morand B
Source :: International journal of pediatric otorhinolaryngology [Int J Pediatr Otorhinolaryngol] 2013 Oct; Vol. 77 (10), pp. 1782-5. Date of Electronic Publication: 2013 Aug 28.
Publication Year :: 2013
Abstract: A 4 year-old female patient was treated for persistent right-sided dacryocystitis and xerostomia. MRI was performed to screen for a dry syndrome; which resulted in the diagnosis of agenesis of the parotid and submandibular glands as well as lacrimal duct malformation. An MRI of each parent was normal. The mother's history revealed 4 days of pyrexia during the 8th week of amenorrhea. This was an isolated case, with no family history, characterized by a febrile episode during pregnancy at the period of main salivary gland genesis. Epigenetic mechanisms could be implicated.<br /> (Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.)