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Synthesis of both enantiomers of 12-methyl-13-tridecanolide and 14-methyl-15-pentadecanolide (muscolide).

Authors :
Noda Y
Mamiya N
Kashin H
Source :
Natural product communications [Nat Prod Commun] 2013 Jul; Vol. 8 (7), pp. 925-8.
Publication Year :
2013

Abstract

Both enantiomers of 12-methyl-13-tridecanolide{(R)-(+)-1, (S)-(-)-1} and 14-methyl-15-pentadecanolide (muscolide) {(R)-(+)-2, (S)-(-)-2} were synthesized from either (S)-(+)- or (R)-(-)-3-bromo-2-methyl-1-propanol 8 as a chiral building block.

Details

Language :
English
ISSN :
1934-578X
Volume :
8
Issue :
7
Database :
MEDLINE
Journal :
Natural product communications
Publication Type :
Academic Journal
Accession number :
23980425