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Increased (18)F-fluoroestradiol uptake in radiation pneumonia.

Authors :
Yang Z
Sun Y
Yao Z
Xue J
Zhang Y
Zhang Y
Source :
Annals of nuclear medicine [Ann Nucl Med] 2013 Dec; Vol. 27 (10), pp. 931-4. Date of Electronic Publication: 2013 Aug 15.
Publication Year :
2013

Abstract

A 54-year-old metastatic breast cancer patient who had undergone chemotherapy and radiotherapy was transferred to our hospital for further treatment. We utilized (18)F-fluoroestradiol (FES) to assess the estrogen receptor (ER) status of metastatic lesions. Interestingly, high accumulation of (18)F-FES in pneumonia caused by radiation was detected. Hence, this draws oncologists' attention to the possible false-positive result of (18)F-FES, which may lead to inappropriate endocrine therapy.

Subjects

Subjects :
Biological Transport
Breast Neoplasms pathology
Breast Neoplasms radiotherapy
False Positive Reactions
Female
Humans
Middle Aged
Neoplasm Metastasis
Positron-Emission Tomography
Radiation Pneumonitis diagnostic imaging
Estradiol metabolism
Fluorine Radioisotopes
Radiation Pneumonitis diagnosis
Radiation Pneumonitis metabolism

Details

Language :
English
ISSN :
1864-6433
Volume :
27
Issue :
10
Database :
MEDLINE
Journal :
Annals of nuclear medicine
Publication Type :
Academic Journal
Accession number :
23949891
Full Text :
https://doi.org/10.1007/s12149-013-0761-1
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