Back to Search
Start Over
IgA/kappa-restricted crystal storing histiocytosis involving the central nervous system characterized by proteomic analysis.
- Source :
-
Clinical neuropathology [Clin Neuropathol] 2014 Jan-Feb; Vol. 33 (1), pp. 23-8. - Publication Year :
- 2014
-
Abstract
- Crystal storing histiocytosis (CSH) is a rare disorder characterized by the accumulation of crystalline material in the cytoplasm of histiocytes. Involvement of the central nervous system (CNS) with CSH is extremely rare. Herein, we report a case of crystal storing histiocytosis involving the CNS. Using immunohistochemistry and mass spectrometry we demonstrate that the disease resulted from an IgA-κ restricted plasma cell dyscrasia. CNS-CSH represents a rare clinicopathologic entity with an indolent course, usually lacking systemic manifestations.
Details
- Language :
- English
- ISSN :
- 0722-5091
- Volume :
- 33
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Clinical neuropathology
- Publication Type :
- Academic Journal
- Accession number :
- 23924753
- Full Text :
- https://doi.org/10.5414/NP300645