[Effects of bromocriptine on the treatment of prolactinomas in male patients and its influences on their sexual function].

Objective: To explore the effect of bromocriptine in the treatment of male patients with prolactinoma and its impacts on their sexual function.
Methods: The clinical data of 29 male patients with prolactinomas treated with Bromocriptine were analysed, International Index of Erectile Function-5 (IIEF-5) was used to assess the sexual function of married patients before and after the treatment of Bromocriptine.
Results: The main clinical symptoms of male patients with prolactinomas were sexual dysfunction, headache and hypopsia, which were released significantly at 6 months after Bromocriptine therapy, with the decrease of serum prolactin (PRL) level (P < 0.05) and the improvement of basal testosterone (T) level (P < 0.05). The total normalization rate of PRL was 82.8%, and total effective rate of Bromocriptine therapy was 100%. According to the assessment of IIEF-5, all the male patients had their sexual function improved in various degree.
Conclusion: Bromocriptine can improve the clinical symptoms of male patients with prolactinoma and their sexual function.