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Green tea catechin induced phagocytosis can be blocked by catalase and an inhibitor of transient receptor potential melastatin 2 (TRPM2).

Authors :
Monobe M
Ema K
Tokuda Y
Maeda-Yamamoto M
Source :
Cytotechnology [Cytotechnology] 2014 Aug; Vol. 66 (4), pp. 561-6. Date of Electronic Publication: 2013 Jul 30.
Publication Year :
2014

Abstract

The major polyphenols in green tea, (-)-epigallocatechin and (-)-epigallocatechin gallate, have been shown to enhance the phagocytic activity of macrophage-like cells; however, the mechanism involved was not clarified. In this study, we have identified that the catechins induced phagocytosis can be blocked by catalase and an inhibitor of transient receptor potential melastatin 2.

Details

Language :
English
ISSN :
0920-9069
Volume :
66
Issue :
4
Database :
MEDLINE
Journal :
Cytotechnology
Publication Type :
Academic Journal
Accession number :
23896702
Full Text :
https://doi.org/10.1007/s10616-013-9618-7