Timing it right: precise ON/OFF switches for Rho1 and Cdc42 GTPases in cytokinesis.

Authors :: Balasubramanian MK
Tao EY
Source :: The Journal of cell biology [J Cell Biol] 2013 Jul 22; Vol. 202 (2), pp. 187-9.
Publication Year :: 2013
Abstract: In many eukaryotes, cytokinesis requires an actomyosin contractile ring that is crucial for cell constriction and new membrane organization. Two studies in this issue (Onishi et al. 2013. J. Cell Biol. http://dx.doi.org.10.1083/jcb.201302001 and Atkins et al. 2013. J. Cell Biol. http://dx.doi.org.10.1083/jcb.201301090) establish that precise activation and/or inactivation of Rho1 and Cdc42 GTPases is important for the correct order and successful completion of events downstream of actomyosin ring constriction in budding yeast.

Subjects :: Cytokinesis
Microtubule-Associated Proteins metabolism
Mitosis
Saccharomyces cerevisiae Proteins metabolism
Saccharomycetales enzymology
cdc42 GTP-Binding Protein, Saccharomyces cerevisiae metabolism
rho GTP-Binding Proteins metabolism

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