Risk factors of liver failure after right-sided hepatectomy.

Authors :: Hirashita T
Ohta M
Iwashita Y
Iwaki K
Uchida H
Yada K
Matsumoto T
Kitano S
Source :: American journal of surgery [Am J Surg] 2013 Sep; Vol. 206 (3), pp. 374-9. Date of Electronic Publication: 2013 Jul 05.
Publication Year :: 2013
Abstract: Background: To prevent hepatic failure after major hepatectomy, it is important to assess preoperative factors related to liver failure.<br />Methods: We examined 80 patients who underwent right-sided hepatectomy. Hyperbilirubinemia, uncontrolled ascites, and prolonged postoperative hospital stay were defined as liver failure after hepatectomy, and these 3 factors were evaluated in relation to clinicopathological and surgical factors.<br />Results: In the 80 patients, hyperbilirubinemia was observed in 10 (12.7%) patients, uncontrolled ascites in 18 (22.5%) patients, and prolonged hospital stay after surgery in 39 (48.8%) patients. Multivariate analyses identified platelet count as a risk factor of hyperbilirubinemia, uncontrolled ascites, and prolonged postoperative hospital stay, and the ratio of remnant liver volume to body surface area (RLV/BSA ratio) as an additional risk factor of hyperbilirubinemia and prolonged postoperative hospital stay.<br />Conclusions: Platelet count and RLV/BSA ratio are useful risk factors for prediction of liver failure after right-sided hepatectomy.<br /> (Copyright © 2013 Elsevier Inc. All rights reserved.)