The use of nitazoxanide against the pathogens Ichthyophthirius multifiliis and Aeromonas hydrophila in silver catfish (Rhamdia quelen).

Authors :: Sutili FJ
Gressler LT
Vargas AC
Zeppenfeld CC
Baldisserotto B
Cunha MA
Source :: Veterinary parasitology [Vet Parasitol] 2013 Nov 08; Vol. 197 (3-4), pp. 522-6. Date of Electronic Publication: 2013 Jun 19.
Publication Year :: 2013
Abstract: The antiparasitic and antibacterial activities of nitazoxanide (NTZ) against Ichthyophthirius multifiliis (Ich) and Aeromonas hydrophila, respectively, were evaluated in silver catfish juveniles (Rhamdia quelen). In the first experiment, fish naturally infected by Ich were treated with different concentrations of NTZ. Fish mortality and the number of trophonts/juveniles were evaluated. In the second experiment, the antimicrobial potential in vitro (MIC test) and preventive potential in vivo against A. hydrophila was evaluated. The treatment with 1.5mgL(-1) NTZ showed the best result against Ich, with a significant reduction of trophonts and fish mortality of 10%. NTZ did not show in vitro activity against A. hydrophila at concentrations tested, but showed a probable preventive activity in vivo. However, these results are preliminary and more studies should be conducted.<br /> (Copyright © 2013 Elsevier B.V. All rights reserved.)

Subjects :: Animals
Anti-Bacterial Agents therapeutic use
Antiparasitic Agents therapeutic use
Catfishes
Ciliophora Infections drug therapy
Fish Diseases parasitology
Gram-Negative Bacterial Infections drug therapy
Gram-Negative Bacterial Infections microbiology
Nitro Compounds
Aeromonas hydrophila
Ciliophora Infections veterinary
Fish Diseases drug therapy
Gram-Negative Bacterial Infections veterinary
Hymenostomatida physiology
Thiazoles therapeutic use

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