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[Diabetes and osteoporosis].
- Source :
-
Revue medicale suisse [Rev Med Suisse] 2013 Jun 12; Vol. 9 (390), pp. 1256, 1258-9. - Publication Year :
- 2013
-
Abstract
- Diabetes alters bone mass and/or quality and increases fracture risk. However, in type 2 diabetes, bone mineral density (BMD) is usually not diminished, pertaining to increased weight and fat mass, which complicates the diagnosis of osteoporosis by DXA (T-score <-2.5). Similarly, estimates of fracture probability by FRAX may underestimate fracture risk in type 2 diabetes. Adequate glycemic control with insulin and/or oral antidiabetics decreases fracture risk, whereas thiazolidinediones increase it. Eventually, osteoporosis drugs such as bisphosphonates and SERMs seem to have similar efficacy in diabetic and non-diabetic patients.
- Subjects :
- Absorptiometry, Photon
Bone Density
Bone Density Conservation Agents therapeutic use
Diabetes Mellitus, Type 2 drug therapy
Humans
Hypoglycemic Agents adverse effects
Hypoglycemic Agents therapeutic use
Osteoporosis diagnosis
Osteoporosis drug therapy
Osteoporotic Fractures prevention & control
Selective Estrogen Receptor Modulators therapeutic use
Diabetes Mellitus, Type 2 complications
Osteoporosis etiology
Osteoporotic Fractures etiology
Subjects
Details
- Language :
- French
- ISSN :
- 1660-9379
- Volume :
- 9
- Issue :
- 390
- Database :
- MEDLINE
- Journal :
- Revue medicale suisse
- Publication Type :
- Academic Journal
- Accession number :
- 23821843