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[Bone structure in rheumatoid arthritis].

Authors :
Ono K
Ohashi S
Tanaka S
Matsumoto T
Source :
Clinical calcium [Clin Calcium] 2013 Jul; Vol. 23 (7), pp. 983-91.
Publication Year :
2013

Abstract

In rheumatoid arthritis (RA) , the osteoclast pathway is activated by abnormal immune conditions accompanied by chronic inflammation, resulting in periarticular osteoporosis and local bone destruction around joints. In addition, multiple factors, including reduced physical activity and pharmacotherapies such as steroids, lead to systemic osteoporosis. These conditions cause decreasing bone mineral density and deterioration of bone quality, and expose patients to increased risk of fracture. Understanding the bone structures of RA and evaluating fracture risk are central to the treatment of RA.

Details

Language :
Japanese
ISSN :
0917-5857
Volume :
23
Issue :
7
Database :
MEDLINE
Journal :
Clinical calcium
Publication Type :
Academic Journal
Accession number :
23811586
Full Text :
https://doi.org/CliCa1307983991