Back to Search Start Over

A novel solvent-free approach to imidazole containing nitrogen-bridgehead heterocycles.

Authors :
Attanasi OA
Bianchi L
Campisi LA
De Crescentini L
Favi G
Mantellini F
Source :
Organic letters [Org Lett] 2013 Jul 19; Vol. 15 (14), pp. 3646-9. Date of Electronic Publication: 2013 Jun 27.
Publication Year :
2013

Abstract

A very simple domino reaction under solvent-free conditions of various pyridine-like heterocycles with 1,2-diaza-1,3-dienes produces in good yields imidazo[1,2-a]pyridines, imidazo[1,2-a]quinolines, and imidazo[2,1-a]isoquinolines. The advantage of this one-pot transformation lies in the use of simple pyridine-like compounds without prefunctionalization of the starting heterocycles.

Details

Language :
English
ISSN :
1523-7052
Volume :
15
Issue :
14
Database :
MEDLINE
Journal :
Organic letters
Publication Type :
Academic Journal
Accession number :
23805986
Full Text :
https://doi.org/10.1021/ol4015267