Relation between serum PAPP-A level and umbilical cord thickness during first trimester of pregnancy.

Authors :: Duran M
Köşüş A
Köşüş N
Turhan NÖ
Source :: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians [J Matern Fetal Neonatal Med] 2014 Mar; Vol. 27 (4), pp. 385-7. Date of Electronic Publication: 2013 Jul 17.
Publication Year :: 2014
Abstract: Purpose: To evaluate the relation between umbilical cord diameter versus pregnancy associated plasma protein-A (PAPP-A) level in first trimester women.<br />Method: Cord diameter were measured and patients were divided into two groups according to frequency distribution analysis as below or above 3.7 mm for free loop diameter (FCD) and below or above 3.4 mm for cord measurement at umbilicus (ACD). Groups were compared with each other.<br />Results: Strong correlations were found between ACD versus PAPP-A.<br />Conclusion: By using strong correlation between ACD versus PAPP-A, it may be possible to reduce unnecessary amniocentesis due to false positive screening results.

Subjects :: Adult
Biomarkers blood
Female
Gestational Age
Humans
Pregnancy
Prospective Studies
Regression Analysis
Umbilical Cord diagnostic imaging
Maternal Serum Screening Tests
Pregnancy Trimester, First blood
Pregnancy-Associated Plasma Protein-A metabolism
Ultrasonography, Prenatal
Umbilical Cord anatomy & histology

Language :: English
ISSN :: 1476-4954
Volume :: 27
Issue :: 4
Database :: MEDLINE
Journal :: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
Publication Type :: Academic Journal
Accession number :: 23795813
Full Text :: https://doi.org/10.3109/14767058.2013.818129

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