Back to Search
Start Over
Reduction of cytotoxicity of natural rubber latex film by coating with PMMA-chitosan nanoparticles.
- Source :
-
Carbohydrate polymers [Carbohydr Polym] 2013 Aug 14; Vol. 97 (1), pp. 52-8. Date of Electronic Publication: 2013 Apr 29. - Publication Year :
- 2013
-
Abstract
- Poly(methyl methacrylate) (PMMA) latex stabilized by chitosan (CS) oligomer was synthesized via the miniemulsion polymerization. By using 1% CS solution (in 0.1M acetic acid), the spherical PMMA-CS particles with an average size of 380 nm were obtained. The positive zeta potentials at pH 2-7 confirmed the presence of CS as the outermost layer of the latex particles. Therefore, these particles directly interacted with the indigenous non-rubbers at the surface of sulphur prevulcanized natural rubber (SPNR) film. The deposition of PMMA-CS particles caused an increase in surface roughness of the coated SPNR film as a function of latex concentration and immersion time. The simple coating of the rubber substrate with PMMA-CS particles effectively reduced the in vitro cytotoxicity on L-929 cells. This study would be, therefore, helpful for development of latex gloves designed for hypersensitive users.<br /> (Copyright © 2013 Elsevier Ltd. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1879-1344
- Volume :
- 97
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Carbohydrate polymers
- Publication Type :
- Academic Journal
- Accession number :
- 23769516
- Full Text :
- https://doi.org/10.1016/j.carbpol.2012.12.078