A parallelism between spectral grading and Gleason grading of malignant prostate tissues.

Authors :: Masilamani V
Alsalhi MS
Devanesan S
Atif M
Rabah D
Farhat K
Pu Y
Alfano RR
Source :: Photodiagnosis and photodynamic therapy [Photodiagnosis Photodyn Ther] 2013 May; Vol. 10 (2), pp. 168-72. Date of Electronic Publication: 2013 Jan 15.
Publication Year :: 2013
Abstract: Gleason score is the most common method of grading the virulence of prostate malignancy and is based on the pathological assessment of morphology of cellular matrix. Since this involves the excision of the tissue, we are working on a new, minimally invasive, non-contact, procedure of spectral diagnosis of prostate malignancy. In this preliminary in vitro study reported here, we have analyzed 27 tissue samples (normal control=7: benign=8: malignant=12) by Stokes' shift spectra (SSS) to establish a one-to-one correspondence between spectral grading and Gleason grading.<br /> (Copyright © 2012 Elsevier B.V. All rights reserved.)

Subjects :: Humans
Male
Neoplasm Grading
Reproducibility of Results
Sensitivity and Specificity
Diagnosis, Computer-Assisted methods
Prostatic Neoplasms pathology
Spectrometry, Fluorescence methods

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