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[Trends in the use of antihypertensive drugs in France from 2002 to 2012: FLAHS surveys].
- Source :
-
Annales de cardiologie et d'angeiologie [Ann Cardiol Angeiol (Paris)] 2013 Jun; Vol. 62 (3), pp. 210-4. Date of Electronic Publication: 2013 May 21. - Publication Year :
- 2013
-
Abstract
- Objective: To evaluate from studies conducted between 2002 and 2012, trends in the use of antihypertensive drugs in France.<br />Method: French League Against Hypertension Survey (FLAHS) were conducted in a representative sample of subjects aged 35 and over living in France. A list including the names for all antihypertensive drugs marketed at the time of each survey made it possible to detail drug therapies employed. Data analysis has taken the patient as a unity. The data obtained in 2002, 2007 and 2012 are subject to this analysis.<br />Results: In 2012, 30% of the French population aged 35 and older was treated with antihypertensive drugs (11.4 million), while 24% were treated in 2002 (8.2 million). On average, prescription of antihypertensive included 1.4 ± 0.7 pills in 2002, 1.5 ± 0.8 in 2007 and 1.8 ± 0.9 in 2012, which corresponds to a pharmacological monotherapy prescribed in 47% of subjects in 2012, a different percentage than in 2007 (46%) and 2002 (56%). Over the period, the percentage of prescriptions of diuretics (41% to 42%) and ACE inhibitors (24% to 23%) and beta-blockers (35% to 36%) is stable, but they are increasing with ARBs (23% to 47%) and calcium antagonists (24% to 34%). The prescriptions of fixed-dose combinations were also increased (19% to 30%). In 2012, fixed-dose combinations included a diuretic (79%), an ARB (65%), an ACEI (23%) and a calcium antagonist (20%). Blood pressure control estimated with home blood pressure monitoring increases from 38% in 2002 to 50% in 2007 and 2012.<br />Conclusion: Changes in the use of antihypertensive drugs in France between 2002 and 2012 led to the prescription of antihypertensive treatment with associations in the majority. ARBs or ACEI are present on 70% of prescriptions with diuretics combined in 80%. Extensive use of fixed-dose combinations with diuretics and ARA2 characterizes this period in which it was observed an increase in blood pressure control in France.<br /> (Copyright © 2013 Elsevier Masson SAS. All rights reserved.)
- Subjects :
- Adult
Aged
Blood Pressure Monitoring, Ambulatory trends
Drug Therapy, Combination trends
Female
France
Health Care Surveys
Humans
Hypertension diagnosis
Male
Middle Aged
Sampling Studies
Surveys and Questionnaires
Treatment Outcome
Adrenergic beta-Agonists therapeutic use
Angiotensin-Converting Enzyme Inhibitors therapeutic use
Antihypertensive Agents therapeutic use
Calcium Channel Blockers therapeutic use
Diuretics therapeutic use
Hypertension drug therapy
Subjects
Details
- Language :
- French
- ISSN :
- 1768-3181
- Volume :
- 62
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Annales de cardiologie et d'angeiologie
- Publication Type :
- Academic Journal
- Accession number :
- 23759733
- Full Text :
- https://doi.org/10.1016/j.ancard.2013.04.011