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[Impaired renal function: be aware of exogenous factors].
- Source :
-
Nederlands tijdschrift voor geneeskunde [Ned Tijdschr Geneeskd] 2013; Vol. 157 (24), pp. A5944. - Publication Year :
- 2013
-
Abstract
- Background: Renal function is currently estimated using the Modification of Diet in Renal Disease (MDRD) formula, which is partly based on the serum creatinine level. Patients with impaired renal function are referred to nephrologists in accordance with the Dutch national transmural agreement for 'Chronic renal impairment'.<br />Case Description: A 54-year-old woman without significant history was referred to analyse a coincidentally found decline in the estimated glomerular filtration rate (eGFR). The patient had no complaints and used no medication except creatine supplements. Additional diagnostic testing showed no abnormalities. After cessation of creatine supplementation, the calculated renal function normalized.<br />Conclusion: Serum creatinine is a reflection of muscle mass. The use of creatine-containing dietary supplements, such as creatine ethyl ester, can influence serum creatinine levels and therefore the eGFR as calculated with the MDRD formula. The use of supplements deserves attention when taking the history.
- Subjects :
- Creatine administration & dosage
Creatine adverse effects
Diet
Female
Humans
Middle Aged
Renal Insufficiency blood
Renal Insufficiency diagnosis
Creatine analogs & derivatives
Creatinine blood
Dietary Supplements adverse effects
Glomerular Filtration Rate physiology
Renal Insufficiency etiology
Subjects
Details
- Language :
- Dutch; Flemish
- ISSN :
- 1876-8784
- Volume :
- 157
- Issue :
- 24
- Database :
- MEDLINE
- Journal :
- Nederlands tijdschrift voor geneeskunde
- Publication Type :
- Academic Journal
- Accession number :
- 23759178