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Water dispersal and functionalization of hydrophobic iron oxide nanoparticles with lipid-modified poly(amidoamine) dendrimers.
- Source :
-
Langmuir : the ACS journal of surfaces and colloids [Langmuir] 2013 Sep 03; Vol. 29 (35), pp. 10973-9. Date of Electronic Publication: 2013 Aug 22. - Publication Year :
- 2013
-
Abstract
- A novel and facile method for water dispersal of hydrophobic iron oxide nanoparticles based on the amphiphilic PAMAM-C12 dendrimer is described. Stable and highly concentrated water dispersions of multifunctional magnetic nanoparticles were obtained with this single-step approach, and showed interesting relaxometric properties for MRI applications. Importantly, this method does not require substitution of the native hydrophobic capping under nonmild reaction conditions, thus preserving the structural and magnetic properties of the nanoparticles, and extending the possibility of conjugation with thermally labile groups.
- Subjects :
- Hydrophobic and Hydrophilic Interactions
Magnetite Nanoparticles ultrastructure
Magnets
Microscopy, Electron, Transmission
Pentanes chemistry
Spectroscopy, Fourier Transform Infrared
Dendrimers chemistry
Ferric Compounds chemistry
Magnetite Nanoparticles chemistry
Surface-Active Agents chemistry
Water chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 1520-5827
- Volume :
- 29
- Issue :
- 35
- Database :
- MEDLINE
- Journal :
- Langmuir : the ACS journal of surfaces and colloids
- Publication Type :
- Academic Journal
- Accession number :
- 23721318
- Full Text :
- https://doi.org/10.1021/la400791a