Nevirapine-Resistant HIV-1 DNA in Breast Milk After Single-Dose Nevirapine With or Without Zidovudine for Prevention of Mother-to-Child Transmission.

Authors :: Gantt S
Payant R
Carlsson J
Micek MA
Blanco AJ
Beck IA
Matunha L
Montoya P
Matediana E
Gloyd S
Frenkel LM
Source :: Journal of the Pediatric Infectious Diseases Society [J Pediatric Infect Dis Soc] 2012 Sep; Vol. 1 (3), pp. 244-9. Date of Electronic Publication: 2012 Jul 03.
Publication Year :: 2012
Abstract: Among 30 human immunodeficiency virus type 1 (HIV-1)-infected women who received single-dose nevirapine (NVP), 17 (57%) had NVP-resistant HIV-1 detected in breast milk. NVP resistance in breast milk persisted for at least 8 months postpartum and was apparently transmitted to at least 1 infant. NVP resistance was detected less often in women who also received zidovudine.<br /> (© The Author 2012. Published by Oxford University Press on behalf of the Pediatric Infectious Diseases Society. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.)

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