Back to Search
Start Over
Late renal sequelae in intravenously treated complicated urinary tract infection.
- Source :
-
European journal of pediatrics [Eur J Pediatr] 2013 Sep; Vol. 172 (9), pp. 1243-8. Date of Electronic Publication: 2013 May 16. - Publication Year :
- 2013
-
Abstract
- Background: The treatment of complicated urinary tract infection in children is still a matter of debate. In our hospital, antimicrobial treatment is initiated intravenously, and the duration of this treatment is adapted according to the results of a Tc-99m dimercaptosuccinic acid (DMSA) scintigraphy.<br />Aim: This study was conducted to evaluate retrospectively the frequency and the importance of late renal sequelae when treating intravenously for 7 days those patients with an abnormal acute DMSA.<br />Methods: A review was conducted of the medical charts of all patients consecutively admitted between 2005 and 2008 with positive urine culture and clinical and biological evidence of complicated urinary tract infection (UTI).<br />Results: There were 144 patients (59 %) with abnormal early DMSA scintigraphy and 98 (41 %) with normal scintigraphy. The median duration of intravenous treatment was 7.0 days in the children with DMSA lesions and 5.0 days in those without lesions. Obvious renal sequelae were observed on late DMSA scintigraphy in 4 (6 %) out of the 65 patients with an abnormal early DMSA who came back for control scintigraphy.<br />Conclusion: Sequelae of acute DMSA lesions observed during complicated UTI treated 7 days intravenously were infrequent. Whether the mode and duration of antimicrobial treatment might explain the low rate of sequelae remains to be demonstrated.
- Subjects :
- Acute Disease
Administration, Intravenous
Adolescent
Ampicillin therapeutic use
Cefotaxime therapeutic use
Child
Child, Preschool
Drug Administration Schedule
Drug Therapy, Combination
Female
Follow-Up Studies
Humans
Infant
Infant, Newborn
Kidney Diseases diagnostic imaging
Kidney Diseases prevention & control
Male
Penicillins therapeutic use
Pyelonephritis diagnostic imaging
Pyelonephritis drug therapy
Pyelonephritis etiology
Radionuclide Imaging
Retrospective Studies
Treatment Outcome
Urinary Tract Infections complications
Urinary Tract Infections diagnostic imaging
Anti-Bacterial Agents therapeutic use
Kidney Diseases etiology
Radiopharmaceuticals
Technetium Tc 99m Dimercaptosuccinic Acid
Urinary Tract Infections drug therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1432-1076
- Volume :
- 172
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- European journal of pediatrics
- Publication Type :
- Academic Journal
- Accession number :
- 23677250
- Full Text :
- https://doi.org/10.1007/s00431-013-2024-5