Prediction of HIV drug resistance based on virologic, immunologic, clinical, and/or adherence criteria in the Stratall ANRS 12110/ESTHER trial in Cameroon.

Authors :: Boullé C
Kouanfack C
Laborde-Balen G
Aghokeng AF
Boyer S
Carrieri MP
Kazé S
Mben JM
Dontsop M
Spire B
Peeters M
Mpoudi-Ngolé E
Delaporte E
Laurent C
Source :: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 2013 Aug; Vol. 57 (4), pp. 604-7. Date of Electronic Publication: 2013 May 10.
Publication Year :: 2013
Abstract: Our study in Cameroonian rural district hospitals showed that the immunologic and clinical failure criteria had poor performance to identify human immunodeficiency virus drug resistance in a timely manner. Switching to second-line antiretroviral therapy after 2 consecutive viral loads ≥5000 copies/mL, as recommended by the World Health Organization, appeared to be the most appropriate strategy.

Subjects :: Adult
CD4 Lymphocyte Count
Cameroon
Female
HIV Infections immunology
HIV Infections pathology
HIV Infections virology
Hospitals
Humans
Male
Middle Aged
Rural Population
Anti-HIV Agents therapeutic use
Decision Support Techniques
Drug Resistance, Viral
HIV Infections drug therapy
Medication Adherence statistics & numerical data
Viral Load

Language :: English
ISSN :: 1537-6591
Volume :: 57
Issue :: 4
Database :: MEDLINE
Journal :: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Publication Type :: Academic Journal
Accession number :: 23667264
Full Text :: https://doi.org/10.1093/cid/cit323

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