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Manzamenone O, new trimeric fatty acid derivative from a marine sponge Plakortis sp.
- Source :
-
Organic letters [Org Lett] 2013 May 17; Vol. 15 (10), pp. 2518-21. Date of Electronic Publication: 2013 May 07. - Publication Year :
- 2013
-
Abstract
- A new structurally unique trimeric fatty acid derivative, manzamenone O (1), was isolated from a marine sponge Plakortis sp. Manzamenone O (1) has a novel skeleton consisting of C-C bonded octahydroindenone and dioxabicyclo[3.3.0]octane moieties and three long aliphatic chains. The structure of 1 was elucidated on the basis of spectroscopic data and conformational analysis. Manzamenone O (1) exhibited antimicrobial activity against Micrococcus luteus, Aspergillis niger, and Trichophyton mentagrophytes.
- Subjects :
- Animals
Anti-Infective Agents isolation & purification
Fatty Acids isolation & purification
Indenes isolation & purification
Magnetic Resonance Spectroscopy
Molecular Structure
Polyketides isolation & purification
Anti-Infective Agents chemistry
Anti-Infective Agents pharmacology
Fatty Acids chemistry
Indenes chemistry
Indenes pharmacology
Plakortis chemistry
Polyketides chemistry
Polyketides pharmacology
Subjects
Details
- Language :
- English
- ISSN :
- 1523-7052
- Volume :
- 15
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- Organic letters
- Publication Type :
- Academic Journal
- Accession number :
- 23651077
- Full Text :
- https://doi.org/10.1021/ol4009975