Gastric cancer chemoprevention: the current evidence.

Authors :: Tan VP
Wong BC
Source :: Gastroenterology clinics of North America [Gastroenterol Clin North Am] 2013 Jun; Vol. 42 (2), pp. 299-316. Date of Electronic Publication: 2013 Mar 13.
Publication Year :: 2013
Abstract: Chemoprevention may form the cornerstone in the management of gastric adenocarcinoma of the future. Helicobacter pylori eradication and aspirin and/or nonsteroidal anti-inflammatory drug therapy have emerged as front-runner chemotherapeutic agents due to the putative pathogenic mechanisms that they address. Before a population-based chemopreventive strategy can be recommended on a large scale, randomized controlled trials with follow-up of more than 10 years of these 2 agents in populations at high gastric adenocarcinoma risk is urgently awaited.<br /> (Copyright © 2013 Elsevier Inc. All rights reserved.)