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[Pronostic value of ureteral location of upper tract urinary carcinoma].
- Source :
-
Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie [Prog Urol] 2013 May; Vol. 23 (6), pp. 399-404. Date of Electronic Publication: 2013 Mar 06. - Publication Year :
- 2013
-
Abstract
- Objectives: The aim of this study was to evaluate the prognostic significance of the ureteral location of the upper tract urinary carcinoma (UTUC).<br />Patients and Methods: Between January 1998 and December 2007, 161 patients with UTUC were operated in our center. Tumors were located on renal pelvis in 51% of cases, on the ureter in 34% of cases and in both locations in 15% of cases. Nephroureterectomy was performed in 79.5% of cases (128/161) whereas a conservative treatment was performed in 20.5% of cases (33/161).<br />Results: In our series, 29.8% of patients had primary bladder cancer and 14.3% had synchronous bladder tumor. At a median follow-up of 42.5 months, 38.6% of patients developed bladder recurrence and 4.8% developed controlateral upper tract tumor. In multivariate analysis, ureteral location and existence of synchronous bladder tumor were independent prognostic factors of bladder recurrence (P=0.009 and P=0.025, respectively). Multivariate analysis retained T-stage and ureteral location as independent prognostic factors in both overall and disease-free survival (P=0.002 and P=0.0008 respectively for ureteral location).<br />Conclusion: Ureteral location was an independent prognostic factor of bladder recurrence and was associated with a poorer prognosis.<br /> (Copyright © 2013 Elsevier Masson SAS. All rights reserved.)
Details
- Language :
- French
- ISSN :
- 1166-7087
- Volume :
- 23
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie
- Publication Type :
- Academic Journal
- Accession number :
- 23628098
- Full Text :
- https://doi.org/10.1016/j.purol.2013.01.025