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Retroperitoneal amyloidosis as the presenting manifestation of Waldenstrom's macroglobulinaemia.
- Source :
-
BMJ case reports [BMJ Case Rep] 2013 Apr 23; Vol. 2013. Date of Electronic Publication: 2013 Apr 23. - Publication Year :
- 2013
-
Abstract
- Retroperitoneal amyloidosis has been described in a few case reports and is typically a secondary manifestation of inflammation or malignancy. We present the case of a 69-year-old man who presented with a large pleural effusion and an incidental retroperitoneal mass in the CT imaging. Further investigation confirmed the diagnosis of amyloid amyloidosis involving the retroperitoneum as well as a concurrent Waldenstrom's macroglobulinaemia. Chemotherapy consistent of drugs active against both the lymphoid and plasma cell components of the disease is the proposed therapy for Waldenstrom's macroglobulinaemia in those patients amenable to receive chemotherapy and can make a difference in the survival.
- Subjects :
- Aged
Biopsy, Needle
Chromatography, Liquid
Diagnosis, Differential
Drug Therapy, Combination
Humans
Incidental Findings
Male
Pleural Effusion diagnostic imaging
Retroperitoneal Space
Tandem Mass Spectrometry
Tomography, X-Ray Computed
Amyloidosis diagnosis
Amyloidosis drug therapy
Antineoplastic Agents therapeutic use
Waldenstrom Macroglobulinemia diagnosis
Waldenstrom Macroglobulinemia drug therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1757-790X
- Volume :
- 2013
- Database :
- MEDLINE
- Journal :
- BMJ case reports
- Publication Type :
- Academic Journal
- Accession number :
- 23616327
- Full Text :
- https://doi.org/10.1136/bcr-2013-009329