Spontaneous dissociation and dislocation of Retisert pellet.

Purpose: To report 4 cases of spontaneous Retisert pellet dislocation.
Design: Retrospective case series.
Methods: Description of cases.
Results: In all 4 cases, the time of Retisert implantation was 3-6 years prior to presentation. One case was complicated by retinal commotio and a retinal tear; another was complicated by corneal endothelial failure, due to dislocation of the pellet into the anterior chamber.
Conclusion: Spontaneous pellet separation may occur with Retisert as a late complication. It is unclear whether these dislocations are from a manufacturing fault or are related to extended intraocular exposure.