A vitamin-responsive mesoporous nanocarrier with DNA aptamer-mediated cell targeting.

Authors :: Li LL
Xie M
Wang J
Li X
Wang C
Yuan Q
Pang DW
Lu Y
Tan W
Source :: Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2013 Jul 04; Vol. 49 (52), pp. 5823-5. Date of Electronic Publication: 2013 Apr 15.
Publication Year :: 2013
Abstract: A smart drug delivery system with cancer cell targeting and bioresponsive controlled drug release has been constructed by taking advantage of a protein-capped mesoporous nanovalve and a DNA aptamer.

Subjects :: Avidin chemistry
Avidin metabolism
Biotin chemistry
Biotin metabolism
Cell Line, Tumor
Cell Survival drug effects
Doxorubicin chemistry
Doxorubicin toxicity
Humans
Porosity
Silicon Dioxide chemistry
Vitamins chemistry
Vitamins metabolism
Aptamers, Nucleotide chemistry
Drug Carriers chemistry
Nanoparticles chemistry

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