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Successful treatment of acquired hemophilia a with rituximab and steroids in a 5-year-old girl.
- Source :
-
Journal of pediatric hematology/oncology [J Pediatr Hematol Oncol] 2014 Mar; Vol. 36 (2), pp. e103-4. - Publication Year :
- 2014
-
Abstract
- Acquired hemophilia A is a very rare, serious bleeding disorder. We describe a 5-year-old female who developed an acquired factor VIII inhibitor, and while under treatment with steroids, had an intestinal perforation with peritonitis and septic shock, making her a poor candidate for further immunosuppression. She was treated with rituximab with rapid, complete eradication of the inhibitor. She represents the first published case of a pediatric patient with acquired hemophilia A successfully treated with rituximab.
Details
- Language :
- English
- ISSN :
- 1536-3678
- Volume :
- 36
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Journal of pediatric hematology/oncology
- Publication Type :
- Academic Journal
- Accession number :
- 23588328
- Full Text :
- https://doi.org/10.1097/MPH.0b013e318286d536