Defined polymer-peptide conjugates to form cell-instructive starPEG-heparin matrices in situ.

Authors :: Tsurkan MV
Chwalek K
Prokoph S
Zieris A
Levental KR
Freudenberg U
Werner C
Source :: Advanced materials (Deerfield Beach, Fla.) [Adv Mater] 2013 May 14; Vol. 25 (18), pp. 2606-10. Date of Electronic Publication: 2013 Apr 10.
Publication Year :: 2013
Abstract: Poly(ethylene glycol)-peptide- and glycosaminoglycan-peptide conjugates obtained by a regio-selective amino acid protection strategy are converted into cell-instructive hydrogel matrices capable of inducing morphogenesis in embedded human vascular endothelial cells and dorsal root ganglia.<br /> (Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.)

Subjects :: Human Umbilical Vein Endothelial Cells cytology
Human Umbilical Vein Endothelial Cells drug effects
Humans
Sulfhydryl Compounds chemistry
Biocompatible Materials chemistry
Biocompatible Materials pharmacology
Heparin chemistry
Peptides chemistry
Polyethylene Glycols chemistry

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