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High use of health services in patients with suboptimal asthma drug regimens: a population-based assessment in British Columbia, Canada.
- Source :
-
Pharmacoepidemiology and drug safety [Pharmacoepidemiol Drug Saf] 2013 Jul; Vol. 22 (7), pp. 744-51. Date of Electronic Publication: 2013 Apr 05. - Publication Year :
- 2013
-
Abstract
- Background: Despite numerous clinical guidelines on asthma management, patients often receive suboptimal drug therapy. This study identified patients who received suboptimal regimens according to the National Heart, Lung and Blood Institute (NHLBI) Guidelines for the Diagnosis and Management of Asthma in a complete population (residents of British Columbia, Canada) and determined the association between patients' regimens and utilization of healthcare services.<br />Methods: A total of 65,345 asthma patients were identified using provincial health service utilization data (including all respiratory-related prescription medication dispensings, physician and hospital visits) for the 2009 fiscal year. Patient-specific regimens of inhaled short-acting bronchodilators (SABA) with or without inhaled corticosteroids (ICS) were categorized as optimal or suboptimal. Logistic regression models were used to determine the association between regimen optimality and health service utilization, adjusted for socioeconomic status, prior year hospital and emergency department (ED) visits for asthma.<br />Results: Patients with suboptimal regimens had significantly greater risk of using health services than patients with optimal regimens of SABA and/or ICS. In particular, adolescents with suboptimal regimens were the most likely to have hospital admissions (odds ratio (OR) 3.8; 95% confidence interval (CI) 1.8-7.8), visit the ED (OR 2.2; 95% CI 1.6-3.1) and be high users of family physician services (OR 5.7; 95% CI 4.0-8.1) compared with patients in other age groups.<br />Conclusions: Suboptimal regimens are associated with significantly high usage of health services. Identifying patients with suboptimal regimens and improving their medication management in accordance with asthma clinical guidelines are likely to result in lower health service utilization.<br /> (Copyright © 2013 John Wiley & Sons, Ltd.)
- Subjects :
- Administration, Inhalation
Adolescent
Adrenal Cortex Hormones administration & dosage
Adult
Anti-Asthmatic Agents administration & dosage
Asthma diagnosis
Asthma epidemiology
British Columbia epidemiology
Bronchodilator Agents administration & dosage
Child
Child, Preschool
Data Mining
Databases, Factual
Drug Prescriptions
Drug Therapy, Combination
Drug Utilization Review
Emergency Service, Hospital
Female
Guideline Adherence
Hospitalization
Humans
Logistic Models
Male
Middle Aged
Odds Ratio
Office Visits statistics & numerical data
Pharmacoepidemiology
Pharmacovigilance
Practice Guidelines as Topic
Practice Patterns, Physicians'
Risk Factors
Socioeconomic Factors
Treatment Outcome
Young Adult
Adrenal Cortex Hormones therapeutic use
Anti-Asthmatic Agents therapeutic use
Asthma drug therapy
Bronchodilator Agents therapeutic use
Health Services statistics & numerical data
Subjects
Details
- Language :
- English
- ISSN :
- 1099-1557
- Volume :
- 22
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- Pharmacoepidemiology and drug safety
- Publication Type :
- Academic Journal
- Accession number :
- 23559540
- Full Text :
- https://doi.org/10.1002/pds.3444