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[Long-term results of radio-surgical treatment of operable carcinoma of the cervix uteri].

Authors :
Lasry S
Cohen-Solal C
Hacene K
Delouche G
Brunet M
Quatramiz A
Guérin P
Source :
Bulletin du cancer [Bull Cancer] 1990; Vol. 77 (4), pp. 355-62.
Publication Year :
1990

Abstract

Four hundred and fifteen women, treated in our institution from 1961 to 1987 for operable carcinoma of the cervix stage I or II, had a radical hysterectomy with pelvic node dissection. Radiotherapy was associated with this surgery in most cases: 90% of the patients received endocavitary radiation, and 30% external radiotherapy, either pre- or post-operatively, in the case of bad prognostic factors. Median follow up was 7 years; overall survival was 77% at 10 years; the rate of local failure is low (36 cases/415 = 8.7%). Multifactorial analysis, using the Cox model, assessed the following independent prognostic factors, significant for the risk of local recurrence (size of the tumor, N +/- , FIGO stage) and for the risk of metastases and death (parametrium invasion, stage, tumor size). Post-operative mortality was 1.2%. Early surgical iatrogeny was easily treated with no long-term sequela, whereas severe complications, due to the association with pelvic irradiation, occurred in 24 out of 124 patients, leading to 7 "illegitimate" deaths.

Details

Language :
French
ISSN :
0007-4551
Volume :
77
Issue :
4
Database :
MEDLINE
Journal :
Bulletin du cancer
Publication Type :
Academic Journal
Accession number :
2354251