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Draft Genome Sequence of Escherichia coli Strain ATCC 23506 (Serovar O10:K5:H4).

Authors :
Cress BF
Greene ZR
Linhardt RJ
Koffas MA
Source :
Genome announcements [Genome Announc] 2013 Feb 28; Vol. 1 (2), pp. e0004913. Date of Electronic Publication: 2013 Feb 28.
Publication Year :
2013

Abstract

We report the 5.101-Mbp high-quality draft assembly of the Escherichia coli strain ATCC 23506 (serovar O10:K5:H4, also known as NCDC Bi 8337-41) genome. This uropathogenic strain, commonly referred to as E. coli K5, produces N-acetyl heparosan, a glycosaminoglycan-like capsular polysaccharide and precursor to the anticoagulant pharmaceutical heparin. Metabolic reconstruction of this genome will enable the prediction of gene deletions and overexpressions that lead to increased heparosan production.

Details

Language :
English
ISSN :
2169-8287
Volume :
1
Issue :
2
Database :
MEDLINE
Journal :
Genome announcements
Publication Type :
Academic Journal
Accession number :
23516192
Full Text :
https://doi.org/10.1128/genomeA.00049-13