PAMAM dendrimer roles in gene delivery methods and stem cell research.

Authors :: Daneshvar N
Abdullah R
Shamsabadi FT
How CW
Mh MA
Mehrbod P
Source :: Cell biology international [Cell Biol Int] 2013 May; Vol. 37 (5), pp. 415-9. Date of Electronic Publication: 2013 Mar 18.
Publication Year :: 2013
Abstract: Nanotechnology has provided new technological opportunities, which could help in challenges confronting stem cell research. Polyamidoamine (PAMAM) dendrimers, a new class of macromolecular polymers with high molecular uniformity, narrow molecular distribution specific size and shape and highly functionalised terminal surface have been extensively explored for biomedical application. PAMAM dendrimers are also nanospherical, hyperbranched and monodispersive molecules exhibiting exclusive properties which make them potential carriers for drug and gene delivery.<br /> (© 2013 International Federation for Cell Biology.)