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[Effect of multi-walled carbon nanotubes on the morphofunctional state of the small intestine cells of mice].
- Source :
-
Gigiena i sanitariia [Gig Sanit] 2012 Nov-Dec (6), pp. 58-61. - Publication Year :
- 2012
-
Abstract
- The experiment was conducted in male mice SBAchS57Vl/6 and Balb/c, which consumed water, obtained from the use of carbon nanotubes. in a free drinking regimen for 2 weeks (mice SBAchS57Vl/6) and 2 months (mice Balb/c) Control group consisted of three groups of animals: intact and mice received fine coal in the same concentrations as under the impact of the nanotubes. Under exposure to the maximal of the studied concentration of carbon nanotubes a significant change in the fine structure of the villi of the small intestine was found in the form of increasing the number of unstructured villi and proliferation of epithelial cells, most pronounced in duration of exposure until 2 months.
- Subjects :
- Animals
Dose-Response Relationship, Drug
Drinking
Intestinal Mucosa ultrastructure
Intestine, Small ultrastructure
Male
Mice
Mice, Inbred BALB C
Mice, Inbred C57BL
Mice, Inbred CBA
Nanotubes, Carbon chemistry
Surface Properties
Time Factors
Water Pollutants, Chemical chemistry
Cell Proliferation drug effects
Intestinal Mucosa drug effects
Intestine, Small drug effects
Nanotubes, Carbon toxicity
Water Pollutants, Chemical toxicity
Subjects
Details
- Language :
- Russian
- ISSN :
- 0016-9900
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Gigiena i sanitariia
- Publication Type :
- Academic Journal
- Accession number :
- 23457999