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[Possible clinical potential in reverting muscular block with sugammadex in anaesthesia and surgery].

Authors :
Øberg E
Claudius C
Source :
Ugeskrift for laeger [Ugeskr Laeger] 2013 Feb 11; Vol. 175 (7), pp. 428-32.
Publication Year :
2013

Abstract

Neuromuscular blockers (NMBs) provide good conditions for endotracheal intubation and surgery. NMBs have been associated with higher morbidity and mortality, mainly due to post-operative residual neuromuscular block. This may become history with the advent of sugammadex - an antidote to the NMB rocuronium - which within 1-3 minutes neutralizes the effects of rocuronium. High-dose rocuronium is now an alternative to suxamethonium in acute or short procedures and in a situation, where ventilation/intubating cannot be performed, sugammadex can reverse the rocuronium blockade within minutes.

Details

Language :
Danish
ISSN :
1603-6824
Volume :
175
Issue :
7
Database :
MEDLINE
Journal :
Ugeskrift for laeger
Publication Type :
Academic Journal
Accession number :
23402253