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An epidemiologic update on hepatitis C infection in persons living with or at risk of HIV infection.

Authors :
Kim AY
Onofrey S
Church DR
Source :
The Journal of infectious diseases [J Infect Dis] 2013 Mar; Vol. 207 Suppl 1, pp. S1-6.
Publication Year :
2013

Abstract

Due to shared routes of transmission, coinfection with both human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV) is relatively common and results in accelerated liver disease, driving morbidity and mortality. Deaths related to HCV now exceed deaths related to HIV in the United States, and co-infected patients bear a significant proportion of that mortality. This burden may be addressed by novel antiviral therapies that promise increased rates of cure or by enhanced access to liver transplantation, but these are costly interventions. Ultimately, the future burden of coinfection is addressed by greater understanding of who is at risk for development of each infection, thus guiding preventive efforts. Key recent reports regarding the US burden of morbidity and mortality due to HCV and groups at risk for coinfection are reviewed, with a focus on recently described HCV occurring among young injection drug users and men who have sex with men. Given the lack of available vaccine against HCV, enhanced detection and surveillance is a vital component of our public health strategy to combat HCV.

Details

Language :
English
ISSN :
1537-6613
Volume :
207 Suppl 1
Database :
MEDLINE
Journal :
The Journal of infectious diseases
Publication Type :
Academic Journal
Accession number :
23390299
Full Text :
https://doi.org/10.1093/infdis/jis927