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The role of a midpotency topical corticosteroid and the clinical relevance of formulation characteristics in the management of commonly encountered eczematous and inflammatory dermatoses in adults and children: focus on the pharmacologic properties of clocortolone pivalate 0.1% cream.
- Source :
-
Journal of drugs in dermatology : JDD [J Drugs Dermatol] 2013 Feb; Vol. 12 (2), pp. s5-s10. - Publication Year :
- 2013
-
Abstract
- Midpotency topical corticosteroids (TCSs) are frequently used for the treatment of common eczematous and inflammatory skin disorders in both adults and children. There are several commercially available products in this category, and many vehicles and formulations for the clinician to choose from. Clocortolone pivalate 0.1% cream is a midpotency TCS formulated in an emollient formulation that has been shown to be effective and well tolerated when used appropriately in the management of several corticosteroid-responsive dermatoses. This article discusses the physiochemical properties of the compound; the characteristics of its emollient cream formulation; the functions of individual excipients; and the efficacy, tolerability, and safety data supporting its use in adults and children, including for facial involvement.
- Subjects :
- Administration, Topical
Adult
Chemistry, Pharmaceutical
Child
Dermatitis, Contact drug therapy
Dermatitis, Contact pathology
Eczema pathology
Face
Fluocortolone administration & dosage
Fluocortolone adverse effects
Fluocortolone therapeutic use
Glucocorticoids administration & dosage
Glucocorticoids adverse effects
Humans
Ointments
Psoriasis drug therapy
Psoriasis pathology
Skin pathology
Skin Diseases pathology
Eczema drug therapy
Fluocortolone analogs & derivatives
Glucocorticoids therapeutic use
Skin Diseases drug therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1545-9616
- Volume :
- 12
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Journal of drugs in dermatology : JDD
- Publication Type :
- Academic Journal
- Accession number :
- 23377405