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Drug carriers in osteoporosis: preparation, drug encapsulation and applications.

Authors :
Miladi K
Sfar S
Fessi H
Elaissari A
Source :
International journal of pharmaceutics [Int J Pharm] 2013 Mar 10; Vol. 445 (1-2), pp. 181-95. Date of Electronic Publication: 2013 Jan 31.
Publication Year :
2013

Abstract

Carriers are largely used to enhance therapy efficiency via the encapsulation of active molecules. The encapsulation enhances the stability of drug molecules, improves the targeting properties and prolongs pharmacological activity via continuous local release of active molecules. The aim of this review is to report the carrier systems used in osteoporosis therapy. This state of the art research has mainly focused on describing all types of carriers used in this area, their elaboration and properties, the drug characteristics used in such specific application, and drug release and efficiency. In this field, various processes have been used in order to obtain well-defined capsules, spheres and more complex carriers. In this exhaustive review, each process is described, illustrated and discussed.<br /> (Copyright © 2013 Elsevier B.V. All rights reserved.)

Details

Language :
English
ISSN :
1873-3476
Volume :
445
Issue :
1-2
Database :
MEDLINE
Journal :
International journal of pharmaceutics
Publication Type :
Academic Journal
Accession number :
23376227
Full Text :
https://doi.org/10.1016/j.ijpharm.2013.01.031