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Annotation: parathyroid hormone and fracture healing.
- Source :
-
Acta orthopaedica [Acta Orthop] 2013 Feb; Vol. 84 (1), pp. 4-6. Date of Electronic Publication: 2013 Jan 31. - Publication Year :
- 2013
-
Abstract
- This annotation describes some early rat studies which conclude that parathyroid hormone (PTH) has more dramatic stimulatory effects on bone repair than on untraumatized bone. It also suggests, based on the effects of PTH on osteoblasts, that it is more likely to accelerate normal fracture healing than to prevent non-union. The only 2 controlled clinical trials that have been published are critically discussed. Although both are encouraging and appear to show acceleration of normal fracture healing, they have methodological shortcomings that preclude definitive conclusions.
- Subjects :
- Animals
Carpal Bones injuries
Fractures, Bone drug therapy
Fractures, Bone physiopathology
History, 20th Century
History, 21st Century
Humans
Orthopedics history
Osteogenesis physiology
Parathyroid Hormone therapeutic use
Pelvic Bones injuries
Rats
Fracture Healing physiology
Parathyroid Hormone physiology
Subjects
Details
- Language :
- English
- ISSN :
- 1745-3682
- Volume :
- 84
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Acta orthopaedica
- Publication Type :
- Academic Journal
- Accession number :
- 23368745
- Full Text :
- https://doi.org/10.3109/17453674.2013.771301