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A probiotics-containing biscuit modulates the intestinal microbiota in the elderly.
- Source :
-
The journal of nutrition, health & aging [J Nutr Health Aging] 2013 Feb; Vol. 17 (2), pp. 166-72. - Publication Year :
- 2013
-
Abstract
- Objectives: Evaluation of the impact of a biscuit containing the probiotics Bifidobacterium longum Bar33 and Lactobacillus helveticus Bar13 on the intestinal microbiota in the elderly.<br />Design: Randomized double-blind placebo-controlled trial.<br />Participants: Thirty-two elderly volunteers living in Italy. The group was composed of 19 women and 13 men aged between 71 and 88 years (mean 76).<br />Intervention: Subjects were randomized in two groups consuming one dose of the probiotics-containing biscuit or placebo once a day for 30 days.<br />Measurements: For each subject the intestinal microbiota was characterized using the phylogenetic microarray platform HTF-Microbi.Array before and after intervention.<br />Results: Our data demonstrated that one-month consumption of a probiotics-containing biscuit was effective in redressing some of the age-related dysbioses of the intestinal microbiota. In particular, the probiotic treatment reverted the age-related increase of the opportunistic pathogens Clostridium cluster XI, Clostridium difficile, Clostridium perfringens, Enterococcus faecium and the enteropathogenic genus Campylobacter.<br />Conclusion: The present study opens the way to the development of elderly-tailored probiotic-based functional foods to counteract the age-related dysbioses of the intestinal microbiota.
Details
- Language :
- English
- ISSN :
- 1760-4788
- Volume :
- 17
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- The journal of nutrition, health & aging
- Publication Type :
- Academic Journal
- Accession number :
- 23364497
- Full Text :
- https://doi.org/10.1007/s12603-012-0372-x