Cerebrospinal fluid (1,3)-β-D-glucan detection as an aid for diagnosis of iatrogenic fungal meningitis.

Authors :: Lyons JL
Roos KL
Marr KA
Neumann H
Trivedi JB
Kimbrough DJ
Steiner L
Thakur KT
Harrison DM
Zhang SX
Source :: Journal of clinical microbiology [J Clin Microbiol] 2013 Apr; Vol. 51 (4), pp. 1285-7. Date of Electronic Publication: 2013 Jan 30.
Publication Year :: 2013
Abstract: This case series highlights our experience with use of the Fungitell assay for quantifying (1,3)-β-d-glucan in cerebrospinal fluid during the current U.S. outbreak of fungal meningitis related to contaminated methylprednisolone acetate. This test may prove a useful adjunct in diagnosis and management of exposed patients.

Subjects :: Adult
Aged
Drug Contamination
Female
Humans
Male
Methylprednisolone administration & dosage
Methylprednisolone adverse effects
Methylprednisolone analogs & derivatives
Methylprednisolone Acetate
Middle Aged
Proteoglycans
Cerebrospinal Fluid chemistry
Iatrogenic Disease
Meningitis, Fungal diagnosis
beta-Glucans cerebrospinal fluid

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